Research Associate in Neuroscience

Studentship Tier 2 Jobs Recruiting in Science/ Research
  • University of Bristol, Tyndall Avenue, Bristol, UK View on Map
  • Post Date: May 22, 2019
  • Apply Before : June 23, 2019
  • Salary: £33,199.00 - £37,345.00 / Yearly
  • Applications 0
  • View(s) 123
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Job Detail

  • Proposed Salary 37,345 Annum
  • Career Level Staff
  • Experience Fresh
  • Gender Any
  • Industry Research & Development
  • Qualifications PhD Requirements

Job Description

We are looking for a self-motivated and talented scientist to study the role of altered microRNA activity on dendritic spine morphology and synaptic function in mouse models for Alzheimer’s disease. The project will build on our recent discovery that Argonaute 2 (Ago2) phosphorylation regulates the local translation of specific mRNAs and is required for structural and functional plasticity (Rajgor et al., EMBO Journal 2018).

 

The work will be based initially in the laboratory of Jon Brown at University of Exeter for in vivo molecular interventions (adenovirus and antagomir injections) and ex vivo slice electrophysiology. This will be followed by biochemical and cell imaging techniques in Jonathan Hanley’s lab in Bristol.

 

Applicants must have a PhD with relevant lab experience, and at least one 1st author article published in a quality peer-reviewed journal.

 

For informal enquiries please contact: Jonathan Hanley, +44(0)117 3311944, [email protected] or Jon Brown, +44(0)1392 725504, [email protected]

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